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Noninvasive Eye Infection Treatment Shows Promise

(NewsUSA) - Those who suffer from eye infections that threaten a person’s vision have a new treatment option that is noninvasive and counters the problem of antibiotic resistance, based on recent research and clinical work.

Many eye infections are caused by multi-drug-resistant strains of bacteria and other pathogens, and standard treatments are limited, according to investigators at the Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine in Florida.

VisiRose, a newly launched, privately-held clinical-stage biotechnology company affiliated with Provectus Biopharmaceuticals (OTCQB: PVCT), is collaborating with Bascom Palmer to commercialize a novel, noninvasive therapy for severe eye infections. The treatment, known as Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT), combines a bioactive synthetic small molecule known as Rose Bengal Sodium with a light-based medical device to help manage eye infections caused by bacteria, fungi, and parasites.

“RB-PDAT represents a consequential solution for patients at risk of vision loss from severe infectious keratitis,” said Dominic Rodrigues, acting CEO of VisiRose. RB-PDAT treatment has been associated with rapid resolution of severe eye infections and improved vision outcomes for patients in clinical studies in the U.S., India, Brazil, and Mexico, according to the company.

“We believe Bascom Palmer’s innovative therapy combines infection-fighting capabilities with vision-preserving benefits, paving the way for a brighter future for those struggling with this challenging condition,” said Rodrigues, who also serves as vice chairman of the board of directors and president of Provectus.

Rose Bengal Sodium, the company’s flagship molecule, has demonstrated effectiveness against multi-drug-resistant Pseudomonas aeruginosa, among other strains, in a laboratory setting. At the Ocular Microbiology and Immunology Group conference in 2023, Bascom Palmer researchers reported that 76% of the first 100 patients treated with RB-PDAT at Bascom Palmer, who had severe eye infections unresponsive to standard treatment,achieved successful vision outcomes, with an average time to resolution of just over 6 months.

In a case series published last year in the medical journal JAMA Ophthalmology of nine adults who experienced severe eye infections caused by contaminated artificial tears, RB-PDAT was effective as an addition to antibiotics and helped improve vision outcomes in two patients who received this new therapy, according to Bascom Palmer researchers: a man in his 40s who came to the emergency department with severe pain and decreased vision in his left eye; and a woman in her 80s with worsening redness and visual loss in her right eye.

“This innovative therapy leverages the power of the versatile rose bengal small molecule to fight infection and offers new hope for preserving vision," Rodrigues said.

RB-PDAT has shown promising results in treating severe eye infections in more than 500 individuals worldwide where standard therapies have failed, according to the company press release. Notably, patients in India and Brazil were treated much earlier with RB-PDAT, receiving the oculat treatment as first-line therapy. “VisiRose has the potential to help fill a critical treatment gap in global eye care, particularly in regions and populations severely impacted by antimicrobial resistance with limited access to medical solutions,” Ed Pershing added, who is chairman of VisiRose’s board of directors and also serves as CEO and chairman of Provectus’s board.

Visit www.visirose.com to learn more.

 

Image caption: Juan Carlos Navia, M.D. at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine, delivering the VisiRose RB PDAT treatment in the clinic.

Snack Smarter With Protein Tortilla Chips

(NewsUSA) - Do you crave crispy, tasty tortilla chips, and want a snack that you and your family can feel good about? If so, then you'll be happy to hear about a new chip that is now available that is rich in plant-based protein but keeps the delicious flavor and texture of your favorite restaurant-style tortilla chips.

SimplyProtein, the same makers of your favorite SimplyProtein bars, makes it easy to enjoy your favorite snacks with the added benefit of protein and without sacrificing taste.

Most people know that eating protein helps the body build muscle strength and repair muscle cells after activity. But protein can also play a role in smarter snacking. In fact, protein digests more slowly compared to carbohydrates, and stimulates appetite hormones that tell your brain that you are full, helping you to eat less.

Adding more protein to your diet is easy, especially if it comes in the form of tasty snacks that you already enjoy. SimplyProtein has just introduced a line of Restaurant-Style Tortilla Chips that are gluten-free, vegan, and kosher, too.

“We believe we’ve cracked the code on indulgent-tasting, better-for-you tortilla chips,” notes Michael Lines, CEO of Wellness Natural Inc., parent company of SimplyProtein. “I’m really proud to have created a new protein-rich snack that tastes so great.”

The tortillas, which come in three flavors—Sea Salt, Hint of Lime, and Hint of Habanero—are made with a unique blend of corn, quality pea protein, and organic sunflower oil, plus other ingredients.

The combination of delicious flavors in a crunchy restaurant-style chip that also provides 7 grams of plant-based protein per 50-gram serving (14 chips) sets SimplyProtein Restaurant-Style Tortilla Chips apart as a superior choice for smart snacking.

Although the chips provide their own zesty flavor and protein power, they make a delicious nacho dish but also pair perfectly with dips and salsas for a winning combination to accompany any social gatherings you may host or attend, like movie nights, girls night in, Super Bowl, fall sports tailgate or other event.

Try your favorite dips, or explore something new, such as this zesty Cowboy Caviar.

Cowboy Caviar

Combine in large bowl:

One 14 oz can black beans, drained
One 14 oz can pinto beans, drained
One 14 oz can of sweet corn, drained
4 bell peppers, finely chopped
2  jalapenos, finely chopped
2 avocados, finely chopped
¾ cup red onion, finely chopped
1 cup black olives, chopped
6 oz crumbled Feta cheese

Dressing:

Combine in a small bowl and drizzle over Cowboy Caviar:

½ cup of olive oil
3 small limes, juiced
3 Tbsp white wine vinegar
3 Tbsp honey
1 Tbsp taco seasoning
salt + pepper to taste
 

Visit simplyprotein.com to learn more.

How Donating Blood Saves and Improves Lives in Your Community

(NewsUSA) - Every 2 seconds, someone in the United States needs blood, and a single donation can save lives. Shortages in the nation’s blood supply can happen any time. Donors, especially those who donate regularly, keep our blood supply stable.

Blood transfusions are essential for some patients undergoing surgery, or who’ve had serious injuries or are dealing with certain medical conditions. While everyone is impacted when there are shortages of blood and blood products, people living in communities with higher numbers of patients with rare blood types or diseases are disproportionately affected.      

Take those with sickle cell disease (SCD), a condition that affects more than 100,000 people in the U.S., the majority of who are Black or of African ancestry. Many people with SCD need blood transfusions throughout their lives but often find it difficult to get the type they need. That’s why Black or African American blood donors are so vital, as 1 in 3 are a match for people with SCD.

While it may seem outdated to think of blood in terms of race – the practice of segregating donated blood by race was discontinued shortly after World War II – scientific studies have found that, to reduce the risk of transfusion complications, some people do require blood or blood products from donors with the same racial or ethnic background.

Most people can give blood, but only 3% of Americans donate each year. If you are in good health, at least 16 or 17 years old (depending on the state), and weigh at least 110 pounds, consider donating. A diverse blood supply ensures that every American has equitable access to blood and blood products. You can make a difference in your community by donating blood and by encouraging others to do the same.

Learn more by visiting the National Heart, Lung, and Blood Institute’s Blood Diseases & Disorders Education Program.

Callout:

Diversity in Blood Types

Most blood types fall into one of the four major groups: A, B, AB, O. Blood donations from all types are always needed. However, some people have rare blood types. Some of the rare blood types for African Americans include U- and Fy (a-b-). For these patients, the U.S. blood supply must be more diverse. The best blood type match for patients with rare blood types often comes from donors of the same race or similar ethnicity.

Cómo la donación de sangre salva y mejora vidas en su comunidad

(NewsUSA) - Cada 2 segundos, alguna persona en los Estados Unidos necesita sangre.  Una sola donación puede salvar vidas. En cualquier momento se puede presentar escasez en el suministro de sangre del país.

Los donantes, especialmente aquellos que donan regularmente, mantienen estable nuestro suministro de sangre. Las transfusiones de sangre son fundamentales para algunos pacientes que se someten a cirugías, han sufrido lesiones graves o padecen ciertas afecciones médicas. Si bien todos nos vemos afectados cuando hay escasez de sangre y productos sanguíneos, las personas que viven en comunidades con una mayor cantidad de pacientes con enfermedades o tipos de sangre poco comunes se ven afectadas de una manera desproporcionada.

Tomemos como ejemplo a las personas con enfermedad de células falciformes (SCD, por su sigla en inglés), una afección que afecta a más de 100,000 personas en los Estados Unidos, la mayoría de las cuales son de raza negra o de ascendencia Africana. Muchas personas con enfermedad de células falciformes necesitan transfusiones de sangre a lo largo de sus vidas, pero a menudo les resulta difícil obtener el tipo que necesitan. Es por eso que los donantes de sangre afroestadounidenses son tan importantes, ya que uno de cada tres es compatible con las personas con enfermedad de células falciformes.

Si bien puede parecer anticuado pensar en la sangre en términos de raza (la práctica de segregar la sangre donada por raza se suspendió poco después de la Segunda Guerra Mundial), los estudios científicos han descubierto que, para reducir el riesgo de complicaciones en las transfusiones, algunas personas requieren sangre o productos sanguíneos de donantes con el mismo origen racial o étnico.

La mayoría de las personas puede donar sangre, pero sólo el 3% de los estadounidenses dona cada año. Si tiene buena salud, al menos 16 o 17 años (dependiendo del estado) y pesa mínimo 110 libras, considere donar. Un suministro de sangre diverso garantiza que todas las personas en los Estados Unidos tengan acceso equitativo a la sangre y a los productos sanguíneos.

Usted puede marcar la diferencia en su comunidad donando sangre y animando a otros a hacer lo mismo.

Obtenga más información visitando el sitio web del Programa de educación sobre enfermedades y trastornos de la sangre (en inglés), del Instituto Nacional del Corazón, los Pulmones y la Sangre.

Callout:

Diversidad de tipos de sangre La mayoría de los tipos de sangre pertenecen a uno de los cuatro grupos principales: A, B, AB y O. Siempre se necesitan donaciones de sangre de todos los tipos. Sin embargo, algunas personas tienen tipos de sangre poco comunes. Algunos de los tipos de sangre poco comunes entre los afroestadounidenses incluyen U- y Fy (a-b-). Para estos pacientes, el suministro de sangre en los Estados Unidos debe ser más diverso. La mejor compatibilidad del tipo de sangre para los pacientes con tipos de sangre poco comunes suele venir de donantes de la misma raza o grupo ético similar.

BookTrib’s Bites: Four Enthralling Autumn Reads

(NewsUSA) - The Amalfi Secret“The Amalfi Secret” by Dean and Catherine Reineking 

When Gabe Roslo arrives in Amalfi, Italy, a long-awaited reunion with his grandparents takes a tragic turn. His beloved grandfather is dead — and a cryptic diary left behind is Gabe’s only clue to the mystery surrounding his sudden death. But what starts as a personal tragedy quickly spirals into a high-stakes international puzzle. 

Teaming up with Anna, a resourceful Roman local, Gabe follows a trail of hidden truths that stretches from the stunning Amalfi coast to the corridors of global power. Secret codes, powerful enemies, and a legacy of deception pull them into a world where nothing is as it seems. With each twist, they are forced to question their allies and uncover dark secrets that could shift the global balance of power. 

Will Gabe and Anna decipher the mystery and reveal the sinister forces at play? Or will they become the next victims of The Amalfi Secret? 

Purchase at https://amzn.to/3HwWiwI

 

Nobody's Legend“Nobody’s Legend” by Jason Ferguson 

Let Go of Who You Were, Rewrite Your Story, and Take Back Your Life. 

What if everything you thought defined you — your past, your failures, your struggles — wasn't the end of your story, but just the beginning? “Nobody's Legend” is a raw, unfiltered journey through adversity, transformation, and the fight to reclaim identity. This is more than a memoir — it's a battle cry for anyone who's ever felt lost, underestimated, or stuck in their own narrative. 

From the highs of athletic success to the darkest depths of addiction and self-doubt, Ferguson lays bare his journey with gripping honesty. Through moments of triumph and despair, he shows that even the hardest setbacks don't define us — it's how we rise from them that does. If you've ever felt like life was slipping away, like the odds were stacked against you, this book will prove that transformation isn't just possible — it's yours for the taking. 

Purchase at https://amzn.to/47D5Lx0

 

The Heart of Bennet Hollow“The Heart of Bennet Hollow” by Joanne Bischof DeWitt 

In this historical retelling of Jane Austen’s “Pride and Prejudice,” an Appalachian farmer’s daughter and a wealthy businessman find a surprising love but must reckon with what divides them. Lizbeth Bennet longs to preserve her family’s farm, a difficult task in their Appalachian coal mining town. But when the mine is put up for sale, a contingent of coal barons descends on the town, among them a young man rumored to be a very rich, eligible bachelor. William Drake arrives focused on business and keeping his distance from the townspeople. As Lizbeth and William continue to cross paths, Lizbeth questions her first impression of the man she believed to be proud and indifferent. Lizbeth must confront her own prejudices ... and decide whether the future she’s always imagined is the one her heart truly wants most after all. 

Purchase at http://bit.ly/3IhttEK

 

Hibernation“Hibernation” by S.J. Epps 

The world has flipped upside down as a new class of citizens has arisen from hibernation and rejects the heterosexual idealism and culture. 

In the aftermath of legalized same-sex marriage in the U.S., two pastors are pulled into a new kind of civil war — those who vehemently oppose the new ruling and those who embrace it wholeheartedly. Lawsuits run rampant. Ministers are imprisoned. Riots ignite. Church doors are shuttered and chained. 

Pastor Sams attends the public rallies and even makes appearances in the courtroom to show his solidarity in standing with Pastor Charles. However, there is a constant fear that threatens their cause and their friendship. As new developments arise and new rebellions crop up, the fabric of America they once relied on starts to shred. The church appears to be losing its voice as the LGBTQ community lunges forth out of hibernation. 

Purchase at https://sjepps.com

Fredro Star to host "Behind The Grind"

Rapper Fredro Starr known for Save the Last Dance and Mosesha hosts "Behind the Grind". Behind The Grind lifts the veil of success and uncovers the principle, perspectives and personal stories of those who have turned life's trails and tribulations into triumphs and inspires us to do the same.

2023 CES Las Vegas: Apple's New Technology 5G Modem Not Ready

Explore Apple's cutting-edge 5G modem technology and discover why it won't debut with the iPhone 15 launch! Delve into the details behind Apple's ambitious plans, including insights into the challenges and timelines shaping this innovative development. Stay informed and subscribe for the latest updates on Apple's groundbreaking advancements in mobile technology.

Warren Buffett's Outlook on Dollar Dominance: Why He Isn't Worried

Warren Buffett isn't at all concerned about de-dollarization, based on his comments in recent years. The famed investor expects the dollar to remain the world's reserve currency for decades to come. However, he's warned against printing too much money and eroding the currency's value.

€1.1mio Research Funding was Awarded to fulfin for its Innovative AI-enabled Credit Scoring for SMEs

fulfin, a fintech start-up, has received a research grant of €1.1mio and has been officially recognized by the Federal Government of Germany for it's innovative AI-enabled real-time credit scoring for SMEs. They have also announced their total investments to the R&D efforts of over €4m, fulfin is a leading provider of flexible financing solutions for digital economy SMEs. It is founded by Nathan Evans and Dr. Alfred Gruber in 2018.

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